Thioglycolic Acid 80% (TGA-80, Japan Origin) is the industry-standard grade of the hair restructuring world’s most essential active — the workhorse concentration that powers the vast majority of professional perm solutions, hair relaxers, and straightening treatments globally. Where the 99% grade is the precision instrument for industrial synthesis and high-concentration formulation work, TGA-80 is the practical, formulation-ready grade that arrives pre-diluted to the concentration most commonly required in finished cosmetic systems, making it easier to handle, measure, and incorporate accurately into professional formulations.
Its Japanese origin is a meaningful quality signal in this category — Japanese-manufactured TGA is consistently recognized for its purity, low odor profile relative to other origins, and reliable batch-to-batch consistency, making it the preferred sourcing choice for professional cosmetic manufacturers who need predictable performance. The chemistry is the same well-established mechanism: the reactive thiol (-SH) group selectively breaks the disulfide bonds (S-S) in hair keratin, making hair pliable and reshapable, followed by neutralization to reform those bonds in the new configuration. Beyond hair restructuring, TGA-80 also finds application in depilatory formulations and as a reducing agent in chemical synthesis processes.
⚠️ Professional Use Only: Strong chemical — handle with appropriate protective equipment (gloves, goggles). Avoid direct skin/eye contact. Must be properly diluted, pH-adjusted, and formulated before use. Not for direct consumer use without formulation. Store in a cool, dry, well-ventilated area.
Key Benefits
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Hair Restructuring Active – breaks disulfide bonds in hair keratin to enable permanent reshaping (curling or straightening)
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Industry-Standard 80% Grade – the most widely used concentration in professional perm and relaxer formulations; practical and formulation-ready
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Japan Origin Quality – recognized for consistent purity, low odor profile, and reliable batch-to-batch performance
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Strong Reducing Agent – versatile beyond hair care; applicable in depilatory formulations and chemical synthesis
Applications
- Hair perming solutions & waving lotions
- Hair straightening & chemical relaxing systems
- Depilatory formulations (in controlled, regulated systems)
- Chemical synthesis & industrial reducing agent applications
Recommended Usage
| Application |
Usage |
| Hair Perm Solutions |
As per formulation guidelines & regulatory limits |
| Hair Straightening Systems |
Controlled professional use — must be neutralized |
| Depilatory Creams |
Low % in regulated formulas — per applicable standards |
Note: Must be correctly diluted, pH-adjusted, and formulated. Follow applicable cosmetic regulations for maximum permitted concentrations in finished products.
Technical Profile
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INCI: Thioglycolic Acid
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Grade: TGA-80 (80% concentration)
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Appearance: Clear to pale yellow liquid
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Type: Organic acid / reducing agent
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Function: Hair restructuring active, disulfide bond reducer
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Origin: Japan
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Use: Cosmetic & Industrial