Methyl Paraben (Uenofine) is one of the most well-established and widely trusted preservatives in cosmetic formulation — and for good reason. As the methyl ester of p-hydroxybenzoic acid, it has a decades-long track record of reliably protecting formulations from the bacteria, yeast, and molds that would otherwise compromise product safety and shelf life. At concentrations as low as 0.1%, it gets to work quietly and effectively, keeping formulations stable from the day they’re made to the day they’re used.
Its real strength lies in its versatility and compatibility. It dissolves readily in warm water or alcohol, integrates smoothly into most cosmetic systems, and performs consistently across a wide pH range (4–8). When combined with Propyl Paraben or other preservatives, it creates a broad-spectrum preservation system that covers the full range of microbial threats — making it a cornerstone ingredient in professional preservation strategies for creams, shampoos, serums, and pharmaceutical preparations alike.
Key Benefits
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Broad-Spectrum Antimicrobial – effective against bacteria, yeast, and mold
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Extends Shelf Life – prevents microbial contamination and product spoilage
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Highly Stable – performs reliably across a wide range of formulation types and pH levels
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Synergistic Preservative – works exceptionally well in combination with Propyl Paraben and other preservatives
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Cost-Effective – proven performance at very low use concentrations
Applications
- Creams, lotions & moisturizers
- Shampoos, conditioners & haircare products
- Face washes, cleansers & toners
- Serums & emulsions
- Pharmaceutical preparations & topical formulations
Recommended Usage Levels
| Application |
Usage Level |
| Cosmetics (standalone) |
0.1% – 0.3% |
| Combined preservative systems |
0.1% – 0.8% (total paraben content) |
Typically dissolved in the water phase (warm) or alcohol phase before incorporation into the formulation.
Technical Profile
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INCI: Methylparaben
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Trade Name: Uenofine
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Appearance: White crystalline powder
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Odor: Odorless
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Solubility: Slightly soluble in water; soluble in alcohol
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Effective pH Range: 4 – 8
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Function: Preservative, antimicrobial agent
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Grade: Cosmetic
Formulation Tips
Dissolve in warm water (above 60°C) or in the alcohol phase for smooth, complete incorporation — avoid adding as a dry powder to cold water as it dissolves slowly. Combine with Propyl Paraben for enhanced broad-spectrum coverage across both gram-positive and gram-negative bacteria, yeast, and mold. Works best in the pH range of 4–8; efficacy decreases above pH 8. Compatible with the vast majority of cosmetic ingredients, including emulsifiers, humectants, and actives.
